Role of Vitamin D Supplementation on Patients of Severe COPD to Reduce Exacerbations.
Background: Vitamin D deficiency is prevalent among patients with chronic obstructive
pulmonary disease (COPD) and comes to be more frequent with increased disease severity.
Low serum 25-hydroxyvitamin D (25-[OH]D) levels have been associated with lower FEV1,
impaired immunologic control and increased airway inflammation which causes frequent
exacerbations of COPD patients.