Muhammad Touhidul Islam Khan1 , S.M. Mostofa Kamal2, Biswas Akhtar Hossain3,Naimul Hoque Shammi3, Mohammed Shahedur Rahman Khan3, A.K.M.Younus Zamal4,Mohammad Mainul Hasan Chowdhury5, Md. Sahen6, Md. Meer Mahbubul Alam7,Pulok Kumar Dey8, Md. Ziaul Karim9, Nihar Ranjan Saha9, Mahmud Masum Attar9,Mohammad Abdur Sakur9, Md. Ali Hossain10, Md. Rashidul Hassan11

Abstract:
Routinely Tuberculous lymphadenitis (TBLN) is diagnosed by fine-needleaspiration
cytology (FNAC) or histopathology. During treatment many cases may
be relapsed, failed or converted to cold abscess. Gene Xpert MTB/RIF is a new
diagnostic tool for bacteriologic evidence of Tuberculous lymphadenitis. Xpert
MTB/RIF can detect TBLN rapidly (within 2 hr) and play role in the categorization
of TB treatment. This study was done at NTRL, NIDCH, Mohakhali, and Dhaka,
Bangladesh from February, 2013 to October, 2013.
Adequate (>0.5ml) amount of fine-needle aspirate (FNA)/biopsy materials were
collected from both new & previously treated suspected TBLN cases. These
specimens were processed for AFB- C/S in MGIT system, DST were done and
sediment from the specimens were used for Xpert MTB/RIF. FNA/biopsy material
was also analyzed by cytology or histopathology for tissue diagnosis. All the
suspected TBLN cases were followed up for at least 2 months after starting anti-TB
drugs. Repeat sample was done for patients with inadequate response to anti-TB
drugs to exclude other diagnosis. Finally, the results were analyzed at SPSS-20
version and the obtained results of Xpert MTB/RIF were compared to CRS.
Thirty (30) cases were selected, among them 15 (50%) were new cases and 15
(50%) were re-treatment cases. There were 10 (33.3%) male and 20 (66.7%) female.
28 (93.3%) cases were TBLN and 2 (6.7%) were other cases; one of them was
Sarcoidosis and the other one was Non Hodgkin Lymphoma. All the patients
were in between 15-54 year age group. Xpert MTB/RIF detected 23 (76.7%) cases
and 7 (23.3%) cases were undetected. There were 4 cases of MDR-TBLN, of which

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