Adult Cystic Fibrosis – A Rare Diagnosis

Md. Abdur Rouf1, Syed Nesar Ahmed2, Md. Saifuddin Khaled3, Mahmud Rahim4, Bipul Kanti Biswas4, Romal Chowdhury2, K.M. Monjurul Alom2, Snehashis Nag5

Abstract
Cystic fibrosis (CF) is a multisystem disease characterized by chronic pulmonary infection, bronchiectasis, exocrine pancreatic insufficiency and elevated sweat chloride level. It is commonly considered as a pediatric disease. But it is now being diagnosed in increasing number of adults due to increased survival from availability of potent antibiotics, nutritional facility and diagnosis of mild cases which were unrecognized previously. CF is rarely reported from Bangladesh and its adult presentation is rarer. Our case, a male from Comilla, Bangladesh was diagnosed to have CF at the age of 35 years. He had chronic cough and wheezing since childhood being treated as asthmatic patient. He had poor nutrional status. Because of chronic cough and expectoration we performed HRCT scan of thorax which revealed bilateral bronchiectasis. He had bilateral maxillary sinusitis.Repeated sweat chloride tests revealed high values suggestive of CF. CF should be considered in differential diagnosis of adults with bronchiectasis and chronic sinusitis or child with chronic respiratory tract infection. High level of awareness
is needed to diagnose CF in Bangladesh, because of its rarity.

Key Words: Cystic fibrosis, Bronchiectasis, Infertility.

 

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