Pulak Kumar Dey1, Ben Noor2, Abdus Shakur Khan2, Roushoni Jahan2, Nasrin Begum2

Abstract:
As much as 25 percent of rheumatic disease patients with systemic symptoms
cannot be definitively diagnosed.1,2 Such patients were first described as having
“collagen” or “connective tissue” diseases, since they shared similar clinical and
pathologic features of widespread inflammation.3-5 Subsequently, these patients
have been considered to have diffuse or undifferentiated (or sometimes early
undifferentiated) connective tissue diseases (UCTD).6 Undifferentiated connective
tissue disease is thought to be a kind of connective disease which shows few clinical
and serological features of autoimmune connective tissue disease but does not
fulfill the diagnostic criteria of well-defined connective tissue disease like rheumatoid
arthritis, SLE, systemic sclerosis etc. Though the prognosis of UCTD is excellent
but occasionally it is aggressive and may affect lung, brain and kidneys.
Keywords: Connective tissue diseases, ILD.

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